UNIVERSAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH

New innovative technique cellulose paper-based smart films: a review

2024-04-12T17:23:01+0530

This document explores the evolution of medicine from ancient practices to modern pharmaceuticals and focuses on the development and application of cellulose paper-based smartFilms for API delivery in disease management. It begins with a historical overview of medical practices and the significance of oral drug administration. The core of this document introduces “SmartFilms” technology, a groundbreaking method to improve the solubility and dissolution rate of weakly water-soluble pharmaceutical drugs, with a focus on API-loaded smart films. The preparation process, sterilization of paper and production of API-loaded smart films and tablets are described in detail. The application of these cellulose paper-based smart films in diabetes management is emphasized, highlighting their enhancement in drug release capabilities and patient-centric advantages. Furthermore, the document envisions future directions in smart film technology, including personalization based on physiological responses and genetic makeup, nanotechnology integration, sustainable materials, and interdisciplinary collaboration. The role of these innovations in advancing the field of drug delivery and their potential to improve patient outcomes is discussed. This comprehensive exploration of cellulose paper-based smart films for API delivery offers valuable insights into the future for the management of diabetes and pharmaceutical advancements.

A Comprehensive Review On Regulatory and Market Study of Cosmeceutical Product in India

2023-04-13T10:43:50+0530

As per the market analysis the cosmetic industry of India was prognosticate to reach a value of about 3 billion U.S dollar in 2012 to 20 billion U.S dollar in 2025. In this article the latest market value of cosmeceutical products in USD has been highlighted in a concise way. Cosmeceutical-grade products are a hybrid of pharmaceutical and cosmetic products but aren’t FDA approved. From the Greek word "kosmetikos" the term "cosmetic" was created. Cosmetic which means any article intended to be rubbed, sprayed or applied to any part of the human body for cleansing and altering the appearance, also includes any article intended for use as a component of cosmetics. A cosmetic product can only be used on the skin's exterior layer; therefore, it cannot effectively treat a particular disease condition. The chemicals like BHA and BHT, Coal Tar Dyes, DEA (Cocamide DEA and Lauramide DEA), Di butyl Phthalate (DBP), parabens, perfume, siloxane etc; are the chemicals that are used while preparing cosmeceutical which possess many health issues. After observing the benefits and growth of cosmeceuticals, as well as the health hazard aspect of the cosmeceutical formulation, there is indeed a need for stringent regulation for control of harmful substances in cosmeceuticals i.e. the safety concern in the product. Not only has the incorporation of newer and modern formulation components in the cosmeceutical products also emphasized on the importance of how these products are regulated in the Indian market.

Survey on comparative study of various marketed anti-dandruff shampoo available in east district of Sikkim

2022-12-26T12:57:36+0530

Purpose: The main purpose of our study is to find most popular and effective antidandruff shampoo in East Sikkim and to know which antidandruff shampoo customers typically choose at the time of purchase based on antidandruff activity, unfavorable effects, availability, MRP, customer satisfaction, and overall shampoo quality.

Methods: A survey-based questionnaire is the method utilized which includes MCQs, likert scale questions.

Results: According to the survey which was carried out in the East district of Sikkim about antidandruff shampoo, Head & Shoulders was the most popular brand, followed by Mamaearth, Himalaya, Dove, and other relevant brands.

Conclusion: There is no shortage in the demand for antidandruff shampoo in the market. The use of a different antidandruff shampoos shows that the consumers are concerned towards their hair problems. Head & Shoulders tops the popularity rank in terms of usage. There is high variability of Head & Shoulders products among its users. People mostly used Head & Shoulders brand products. They only switched over to another brand in case of non-availability.

Preparation and evaluation of lipstick by using different ratios of oils and wax bases

2023-02-11T12:41:53+0530

Formulations for lipstick are used to enhance the appearance of lips. Natural elements like colors, waxes, oils, and emollients were used to create lipstick, a cosmetic product. There are several different types of lipstick that are only worn by women. Pink lipstick is created by blending red and white titanium dioxide. The two types of pigments utilized are organic and inorganic. One of the main cosmetics that women use is lipstick. The primary topics of this review include lipstick, natural waxes, evaluation, and lipstick flaws.

Heterocyclic compounds: as Antidiabetic drugs

2023-04-12T09:17:39+0530

Diabetes can have long-term consequences by causing damage to essential organs, blood vessels, and nerves. Diabetes prevalence continues to climb internationally, with poorer nations bearing the brunt of the burden. Diabetes mellitus is a condition characterised by insufficient glucose management in the blood. Type 1 diabetes, type 2 diabetes, neonatal diabetes, maturity-onset diabetes of the young, gestational diabetes and steroid-induced diabetes are all subtypes. Since sickness is essentially because of the shortfall of insulin, insulin organization through day to day infusions, or an insulin siphon, is the backbone of therapy. Traditional oral drug therapy is described in the paper. In type 2 diabetes mellitus, diet and exercise might be satisfactory medicines, particularly at first. Different treatments might insulin awareness or increment insulin emission by the pancreatic islets. The particular classes for drugs incorporate thiazolidinediones, biguanides, sulfonylureas, dipeptidyl peptidase-IV inhibitors, alpha-glucosidase inhibitors, glucagon like-peptide-1 agonist, sodium-glucose carrier 2 inhibitors and meglitinides. And peer review of many heterocyclic moieties used as synthesis of anti-diabetic compound is described. Heterocyclic moieties like oxazole, thiazole, pyrrole, piperazine and many more are explained for generation of antidiabetic compounds having a significant therapeutic effect their structures are also provided and if structure activity relationship is explained for the heterocyclic compounds mentioned and what functional group changes can be possible for significant antidiabetic effect. As several of the pharmacological candidates mentioned show potential as an effective anti-diabetic chemotherapy, this study provides a platform for future medication design and development targeting diabetes treatment (i.e. optimization by structural derivatization).