An alternate method for nasal medicine delivery is in-situ gel

Authors

  • Sumit Sinha Mahapatra Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim 737136
  • Arif Mahammad Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim 737136
  • Sanjib Bahadur Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim 737136
  • Pragya Baghel Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim 737136

DOI:

https://doi.org/10.61114/UJPSR.8.2.2022.8-12

Keywords:

Intranasal, GIT, Orally, Uncomfortable

Abstract

Nasal medication administration has been used for therapeutic and recreational purposes since the dawn of civilization. The importance of and interest in the systemic effects of medications taken orally has grown over the past few decades. Medications administered intra-nasally provide an intriguing option to the parenteral route, which can occasionally be uncomfortable. These might involve avoiding pre-systemic release in the digestive tract and eliminating the first-pass effect (GIT), necessitating the use of a tiny dose of a specific medicine. Lowering the dose will lessen the negative effects and, ultimately, lower the cost of the medication. The likelihood for intranasal medication delivery to overcome certain significant drawbacks is linked with the other stated routes making it the most exciting path for drug administration. This review covered how in situ gel became more popular than previous nasal administration forms.

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Published

31-12-2022

How to Cite

Mahapatra, S. S., Mahammad, A., Bahadur, S., & Baghel, P. (2022). An alternate method for nasal medicine delivery is in-situ gel. UNIVERSAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 8(2), 8–12. https://doi.org/10.61114/UJPSR.8.2.2022.8-12

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