Anti-aging activity of various topical nano herbal formulations
Keywords:
Aging, anti-aging, herbal formulation, antioxidant, nanotechnology, transdermal deliveryAbstract
We utilised a variety of medicinal plants because, as we all know, they are excellent providers of many vitamins and minerals that are used to treat a variety of ailments, including ageing and other disorders. The majority of plants include a combination of elements that work together synergistically to increase a drug's ability to treat problems associated with ageing. Natural herbal plant formulations were created by combining various plant extracts or ingredients in varying proportions to create cream, oil, gel, and lotion. Although helpful in the treatment of ageing issues and a number of ailments, it also has some restrictions when used topically. Some of these restrictions include the potential for localised skin irritation, poor drug permeability through the skin, the difficulty of absorbing drugs with larger particle size and higher molecular weight through the skin, the possibility of toxic reactions following application, or the possibility that drugs may be denatured by the enzymes found in the epidermis. With the advancement of innovative technologies like nanotechnology, we can now get beyond the drawbacks of conventional topical formulations. The typical properties of products created with the aid of nanotechnologies include biocompatibility, biodegradability, a longer duration of action, the ability to perform numerous functions, the ability to modify drug release, potential targeting, and reduced toxicity, among many others. The purpose of the present review is to study different medicinal plants having anti-ageing activity. The review mainly focusses on various nanotechnology based herbal formulations which can be use to enhance the effectiveness in anti-ageing activity. However, nanotechnology has established that it can provide tools to overcome the problem associated with herbal medicine
References
Margaret P. Original Research Article Original Research Article Open Access 2017;07:17531–5.
Sahatpure NS, Daud FS. Anti Ageing Herbs-A Review. Ijsdr 2018;3:53.
sahu kumar.pdf n.d.
Chakraborty A, Sahoo M, Roy SD, Dasgupta RK. Anti-Ageing Natural Herbs: a Systemic Review. Indian Res J Pharm Sci 2018;5:1589–98. https://doi.org/10.21276/irjps.2018.5.3.4.
Alğin Yapar E. Herbal cosmetics and novel drug delivery systems. Indian J Pharm Educ Res 2017;51:S152–8. https://doi.org/10.5530/ijper.51.3s.3.
Souto EB, Fernandes AR, Martins-Gomes C, Coutinho TE, Durazzo A, Lucarini M, et al. Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals. Appl Sci 2020;10. https://doi.org/10.3390/app10051594.
Santos AC, Morais F, Simões A, Pereira I, Sequeira JAD, Pereira-Silva M, et al. Nanotechnology for the development of new cosmetic formulations. Expert Opin Drug Deliv 2019;16:313–30. https://doi.org/10.1080/17425247.2019.1585426.
Vaiserman A, Koliada A, Zayachkivska A, Lushchak O. Nanodelivery of Natural Antioxidants: An Anti-aging Perspective. Front Bioeng Biotechnol 2020;7:1–19. https://doi.org/10.3389/fbioe.2019.00447.
Aithal PS, Aithal S. Nanotechnology Innovations and Commercialization-Opportunities, Challenges & Reasons for Delay. Int J Eng Manuf 2016;6:15–25. https://doi.org/10.5815/ijem.2016.06.02.
Kaul S, Gulati N, Verma D, Mukherjee S, Nagaich U. Role of Nanotechnology in Cosmeceuticals: A Review of Recent Advances. J Pharm 2018;2018:1–19. https://doi.org/10.1155/2018/3420204.
Fytianos G, Rahdar A. Nanomaterials in Cosmetics : Recent Updates 2020:1–16.
Remedies S. Role of Nanotechnology in Skin Remedies n.d. https://doi.org/10.1007/978-981-10-5493-8.
Hameed A, Fatima GR, Malik K, Muqadas A. Scope of Nanotechnology in Cosmetics: Dermatology and Skin Care Products 2019;2019:9–16. https://doi.org/10.26655/jmchemsci.2019.6.2.
Sumaiyah S, Meyliana. Formulation and Evaluation of Skin Anti-aging Nanocream Containing Canola (Brassica napus L.) Oil. Indones J Pharm Clin Res 2021;4:47–58. https://doi.org/10.32734/idjpcr.v4i1.5821.
Mahawar V, Patidar K, Joshi N. Development and Evaluation of Herbal Antiaging Cream Formulation Containing Annona Squamosa Leaf Extract. Asian J Pharm Clin Res 2019;12:210–4. https://doi.org/10.22159/ajpcr.2019.v12i2.29026.
Kaur CD, Saraf S. Topical vesicular formulations of Curcuma longa extract on recuperating the ultraviolet radiation-damaged skin. J Cosmet Dermatol 2011;10:260–5. https://doi.org/10.1111/j.1473-2165.2011.00586.x.
Ahmed AA, Nath B. Formulation and in Vitro Evaluation of Poly-Herbal Anti-Ageing Face Cream of Coriandrum Sativum and Rose Hip Oil. Int J Curr Pharm Res 2017;9:75. https://doi.org/10.22159/ijcpr.2017v9i4.20961.
Jadoon S, Karim S, Asad MHH Bin, Akram MR, Kalsoom Khan A, Malik A, et al. Anti-aging potential of phytoextract loaded-pharmaceutical creams for human skin cell longetivity. Oxid Med Cell Longev 2015;2015. https://doi.org/10.1155/2015/709628.
Shackleton C. Use of marula products for domestic and commercial purposes : Synthesis of key findings from three sites in southern Africa Sheona Shackleton , Saskia den Adel , Tania McHardy and Charlie Shackleton Produced by : Environmental Science Department , Funded. Environ Sci Dep Rhodes Univ Grahamstown, South Africa 2002.
Chaikul P, Kanlayavattanakul M, Somkumnerd J, Lourith N. Phyllanthus emblica L. (amla) branch: A safe and effective ingredient against skin aging. J Tradit Complement Med 2021;11:390–9. https://doi.org/10.1016/j.jtcme.2021.02.004.
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