Comparative study of different binder concentration of aloe as natural binder in the preparation of paracetamol tablet

Authors

  • Soutik Sarkar Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Samrat Chowdhury Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Samuel Chettri Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Samikcha Rai Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Sudishna Das Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Sudip Das Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136

DOI:

https://doi.org/10.61114/UJPSR.8.2.2022.19-21

Keywords:

Aloe vera, mucilage, paracetamol, binder, economical

Abstract

Natural binders like different starches, gums, mucilage dried fruits possess binding capacity and are much safer and economical than polymers like PVP. The aim of the work was to compare different concentration of Aloe vera mucilage as a binder for preparation of Paracetamol tablet. The results of the study revealed that 5% aloes mucilage concentration shows good drug release pattern for conventional oral tablets of Paracetamol. Thus, it can be concluded that 5% Aloe vera mucilage may be used as a binder in tablet formulation and possess a high potential for substitution for other more expensive binders.

References

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Adebowale BO, Oluwatomi O, Gbenga BL. Compressional properties of metronidazole tablet formulations containing aloe vera as binding agent. Int J Pharm Pharm Sci 2014;6:261–4.

Pant S, Sharma K, Malviya R. Evaluation of Different Concentration of Binders on the Dissolution Profile of Paracetamol Tablets. Adv Biol Res (Rennes) 2015;9:82–5. https://doi.org/10.5829/idosi.abr.2015.9.2.9343.

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Published

31-12-2022

How to Cite

Sarkar, S., Chowdhury, S., Chettri, S., Rai, S., Das, S., & Das, S. (2022). Comparative study of different binder concentration of aloe as natural binder in the preparation of paracetamol tablet. UNIVERSAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 8(2), 19–21. https://doi.org/10.61114/UJPSR.8.2.2022.19-21

Issue

Vol. 8 No. 2 (2022)

Section

Articles

License

Copyright (c) 2023 Soutik Sarkar, Samrat Chowdhury, Samuel Chettri, Samikcha Rai, Sudishna Das, Sudip Das

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.