Formulation of Metformin Hydrochloride tablet using fenugreek seed mucilage.

Authors

  • Sudishna Das Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Subham Paul Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Subhankar Ghosh Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Subrata Ghosh Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Subham Kumar Gupta Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136
  • Soutik Sarkar Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, East Sikkim, India 737136

DOI:

https://doi.org/10.61114/UJPSR.8.2.2022.22-24

Abstract

This research work aims to develop Metformin Hydrochloride tablet using fenugreek seed mucilage. Fenugreek seed has antidiabetic activity. It also contains a major proportion of mucilage. The mucilage was extracted by soaking the powdered seed into water for 12-14 hours then, after filtration the filtrate was mixed with ethanol and the precipitated mucilage was dried and grounded into powder. The tablet utilizing the mucilage as excipient was prepared by wet granulation method. The tablets were subjected to various tests. The evaluatory parameters of tablets were found to be within the limits as per Indian Pharmacopoeia. 

References

Bahadur S, Roy A, Baghel P, Chanda R. Formulation of Glipizide Tablets using Fenugreek Seed Mucilage: Optimization by Factorial Design. Asian J Pharm 2016;10:S662–8.

https://doi.org/10.22377/ajp.v10i04.906.

World Health Organization. 2016.

Indian Pharmacopoeia 2010;1:192

Khar RK, Vyas SP, Ahmad FJ. The theory and practice of industrial pharmacy. Fourth Edi. CBS Publishers & Distributors Pvt Ltd

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Published

31-12-2022

How to Cite

Das, S., Paul, S., Ghosh, S., Ghosh, S., Kumar Gupta, S., & Sarkar, S. (2022). Formulation of Metformin Hydrochloride tablet using fenugreek seed mucilage. UNIVERSAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 8(2), 22–24. https://doi.org/10.61114/UJPSR.8.2.2022.22-24

Issue

Vol. 8 No. 2 (2022)

Section

Articles

License

Copyright (c) 2023 Sudishna Das, Subham Paul, Subhankar Ghosh, Subrata Ghosh, Subham Kumar Gupta, Soutik Sarkar

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.